Allow manufacturer’s instructions for changing (or cleaning) air filters in air handlers/furnaces and other home comfort equipment. Some air cleaners require only an annual filter change, while others need more frequent replacement.
Maintaining proper humidity levels can greatly reduce airborne allergens. Make sure pans and coils of humidification/dehumidification unit are clean and free of debris.
Regularly clean your return grills to prevent dust and debris from accumulating in ducts and clogging filters.